Prof. Minxin Guan's group published on Nucleic Acids Research
In this report, we investigated the molecular mechanism underlying a deafness-associated m.7516delA mutation affecting the 5′ end processing sites of mitochondrial tRNAAspand tRNASer(UCN). Anin ...
READ MOREProf. Minxin Guan's group published on The Journal of Clinical Investigation
Leber’s hereditary optic neuropathy (LHON) is a maternally inherited eye disease. X-linked nuclear modifiers were proposed to modify the phenotypic manifestation of LHON-associated mitochondrial...
READ MOREProf. Minxin Guan's group published on Nucleic Acids Research
In this report, we investigated the molecular mechanism underlying a deafness-associated m.7516delA mutation affecting the 5′ end processing sites of mitochondrial tRNAAspand tRNASer(UCN). Anin ...
READ MOREProf. Minxin Guan's group published on The Journal of Clinical Investigation
Leber’s hereditary optic neuropathy (LHON) is a maternally inherited eye disease. X-linked nuclear modifiers were proposed to modify the phenotypic manifestation of LHON-associated mitochondrial...
READ MOREProf. Minxin Guan's group published on Nucleic Acids Research
Mitochondrial tRNA processing defects were associated with human diseases but their pathophysiology remains elusively. The hypertension-associated m.4401A>G mutation resided at a spacer between mit...
READ MOREProf. Minxin Guan's group published on Nucleic Acids Research
GTPBP3 is a highly conserved tRNA modifying enzyme for the biosynthesis of τm5U at the wobble position of mitochondrial tRNAGlu, tRNAGln, tRNALys, tRNATrpand tRNALeu(UUR). The previous investigati...
READ MOREProf. Xiaohang Yang's group published on Aging Cell
By the end of neurogenesis in Drosophila pupal brain neuroblasts (NBs), nuclear Prospero (Pros) triggers cell cycle exit and terminates NB lifespan. Here, we reveal that in larval brain NBs, an intrin...
READ MOREZJU-Tencent Games Joint Lab for Intelligent Graphics Innovative Technology set up
By the end of neurogenesis in Drosophila pupal brain neuroblasts (NBs), nuclear Prospero (Pros) triggers cell cycle exit and terminates NB lifespan. Here, we reveal that in larval brain NBs, an intrin...
READ MORECongratulation our ZJU graduates!
By the end of neurogenesis in Drosophila pupal brain neuroblasts (NBs), nuclear Prospero (Pros) triggers cell cycle exit and terminates NB lifespan. Here, we reveal that in larval brain NBs, an intrin...
READ MOREUltraviolet radiant energy-dependent functionalization regulates cellular behaviors on TiO2 nanodots
By the end of neurogenesis in Drosophila pupal brain neuroblasts (NBs), nuclear Prospero (Pros) triggers cell cycle exit and terminates NB lifespan. Here, we reveal that in larval brain NBs, an intrin...
READ MORE
